Last Wednesday a Go! flight from Honolulu to Hilo overshot the airport by 15 miles before turning and landing safely. Air traffic controllers were unable to reach the plane for 25 minutes, leading people to speculate whether or not the pilots drowsed off en route.
Most commercial flights between Honolulu and Hilo have an autopilot function, but towards the end of a flight the pilot needs to manually set a lower altitude for landing. If you fall asleep, doing so can be difficult. Maybe the stewardesses need to serve more coffee next time.